transthyretin amyloidosis

AATR amyloidosis

transthyretin amyloidosis (Wikipedia)
Familial amyloid polyneuropathy
Classification and external resources
OMIM 105210
eMedicine article/335301

Familial amyloid polyneuropathy (FAP), also called transthyretin-related hereditary amyloidosis, transthyretin amyloidosis abbreviated also as ATTR (hereditary form), or Corino de Andrade's disease, is an autosomal dominantneurodegenerative disease. It is a form of amyloidosis, and was first identified and described by Portuguese neurologist Mário Corino da Costa Andrade, in 1952. FAP is distinct from senile systemic amyloidosis (SSA), which is not inherited, and which was determined to be the primary cause of death for 70% of supercentenarians who have been autopsied.

FAP can be ameliorated by liver transplantation.