Primary lateral sclerosis

kelemahan yang semakin memberat pada otot yang tidak dapat digerakkan dengan kesadaran (otot involunter).

Primary lateral sclerosis (Wikipedia)
Primary lateral sclerosis
Classification and external resources
Specialty neurology
ICD-10 G12.2
ICD-9-CM 335.24
OMIM 606353
DiseasesDB 29150
eMedicine neuro/324
MeSH D016472

Primary lateral sclerosis (PLS) is a rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles. PLS belongs to a group of disorders known as motor neuron diseases. Motor neuron diseases develop when the nerve cells that control voluntary muscle movement degenerate and die, causing weakness in the muscles they control.

PLS only affects upper motor neurons. There is no evidence of the degeneration of spinal motor neurons or muscle wasting (amyotrophy) that occurs in amyotrophic lateral sclerosis (ALS).