amygdalin

glikosida sianogenetik (l-mandelonitril-β-gentiobiosida) yang ditemukan dalam biji-bijian dan bagian tanaman lain dari buah kenari yang pahit dan anggota lain famili Rosaceae, sering kali menjadi penyebab keracunan sianida pada hewan yang memakannya dalam jumlah banyak. Diuraikan oleh hidrolisis enzimatik menjadi glukosa, benzaldehida, dan asam hidrosianat. Lihat juga Laetrile dan laetrile.

Merriam-Webster Online Dictionary
amygdalin (noun)
a white crystalline cyanogenetic glucoside CHNO found especially in the seeds of the apricot, peach, and bitter almond - 20 27 11 compare laetrile
amygdalin (Wikipedia)
Amygdalin
Amygdalin structure.svg
Amygdalin-from-xtal-3D-balls.png
Names
IUPAC name
[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy](phenyl)acetonitrile
Identifiers
3D model (Jmol)
ChEBI
ChemSpider
ECHA InfoCard 100.045.372
MeSH Amygdalin
UNII
Properties
C20H27NO11
Molar mass 457.429
Melting point 223-226 °C(lit.)
H2O: 0.1 g/mL hot, clear to very faintly turbid, colorless
Hazards
Safety data sheet A6005
GHS pictograms The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word Warning
H302
P264, P270, P301+312, P330, P501
NFPA 704
Flammability code 0: Will not burn. E.g., waterHealth code 1: Exposure would cause irritation but only minor residual injury. E.g., turpentineReactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogenSpecial hazards (white): no codeNFPA 704 four-colored diamond
Related compounds
Related compounds
Vicianin, laetrile, prunasin, sambunigrin
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Amygdalin (from Ancient Greek: ἀμυγδαλή amygdálē "almond") is a poisonous cyanogenic glycoside found in many plants, but most notably in the seeds (kernels) of apricot, bitter almonds, apple, peach, and plum.

Since the early 1950s, both amygdalin and a modified form named laetrile have been promoted as alternative cancer treatments, often using the misnomer Vitamin B17. But studies have found them to be clinically ineffective in the treatment of cancer, as well as potentially toxic or lethal when taken by mouth, due to cyanide poisoning. Neither amygdalin nor laetrile is a vitamin.

The promotion of laetrile to treat cancer has been described in the medical literature as a canonical example of quackery, and as "the slickest, most sophisticated, and certainly the most remunerative cancer quack promotion in medical history."