amodiaquine hydrochloride

garam dihidroklorida dihidrat dan amodiaquine, kerjanya sama dengan bentuk basanya, diberikan secara oral dalam pengobatan malaria.

amodiaquine hydrochloride (Wikipedia)
Clinical data
Trade names Amdaquine, Amobin, others
AHFS/ International Drug Names
ATC code
CAS Number
PubChem CID
ECHA InfoCard 100.001.518
Chemical and physical data
Formula C20H22ClN3O
Molar mass 355.861 g/mol
3D model (Jmol)

Amodiaquine (ADQ) is a medication used to treat malaria, including Plasmodium falciparum malaria when uncomplicated. It is recommended to be given with artesunate to reduce the risk of resistance. Due to the risk of rare but serious side effects, it is not generally recommended to prevent malaria.

The side effects of amodiaquine are generally minor to moderate and are similar to those of chloroquine. Rarely liver problems or low blood cell levels may occur. When taken in excess headaches, trouble seeing, seizures, and cardiac arrest may occur. While not extensively studied as of 2007, it appeared to be safe in pregnancy. Amodiaquine is a 4-aminoquinoline compound related to chloroquine.

Amodiaquine was first made in 1948. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost is about 0.01 USD per dose as of 2014. While not available in the United States, it is widely available in Africa.