Aminophylline

Garam teofilin, dipakai terutama untuk bronkodilator.

Merriam-Webster Online Dictionary
aminophylline (noun)
a theophylline derivative CHNO used especially to stimulate the heart in congestive heart failure and to dilate the air passages in respiratory disorders (as asthma) - 16 24 10 4
Aminophylline (Wikipedia)
Aminophylline
Aminophylline.svg
Clinical data
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a601015
Pregnancy
category
  • AU: A
  • US: C (Risk not ruled out)
Routes of
administration
By mouth, IV
ATC code
Legal status
Legal status
Pharmacokinetic data
Protein binding 60%
Biological half-life 7–9 hours
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard 100.005.696
Chemical and physical data
Formula C16H24N10O4
Molar mass 420.427 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate.

Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD. It is used off-label as a reversal agent during nuclear stress testing. Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor.