merek dagang untuk preparat doksorubisin hidroklorida.

Adriamycin (Wikipedia)
Doxorubicin 3D ball.png
Clinical data
Pronunciation /ˌdɒksəˈrbsɪn/
Trade names Adriamycin, Doxil, Caelyx, Myocet, others
AHFS/ Monograph
MedlinePlus a682221
  • AU: D
  • US: D (Evidence of risk)
Routes of
intravenous, intravesical
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailability 5% (by mouth)
Protein binding 75%
Metabolism Liver
Biological half-life Triphasic; 12 minutes, 3.3 hours, 30 hours. Mean: 1-3 hours
Excretion Urine (5-12%), faeces (40-50%)
CAS Number
PubChem CID
ECHA InfoCard 100.041.344
Chemical and physical data
Formula C27H29NO11
Molar mass 543.52 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Doxorubicin, sold under the trade names Adriamycin among others, is a chemotherapy medication used to treat cancer. This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. It is often used together with other chemotherapy agents. Doxorubicin is given by injection into a vein.

Common side effects include hair loss, bone marrow suppression, vomiting, rash, and inflammation of the mouth. Other serious side effects may include allergic reactions such as anaphylaxis, heart damage, tissue damage at the site of injection, radiation recall, and treatment-related leukemia. People often experience red discoloration of the urine for a few days. Doxorubicin is in the anthracycline and antitumor antibiotic family of medications. Its works in part by interfering with the function of DNA.

Doxorubicin was approved for medical use in the United States in 1974. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 3.88 to 32.79 USD per 50 mg vial. In the United Kingdom this amount costs the NHS about £100.12. Versions that are pegylated and in liposomes are also available; however, are more expensive. Doxorubicin was originally made from the bacteria Streptomyces peucetius.