turunan semisintetik ampicillin yang efektif melawan spektrum luas bakteri gram-positif dan gram-negatif; terutama digunakan untuk pengobatan infeksi galur peka Haemophilus influenzae, Escherichia coli, Proteus mirabilis, Neisseria gonorrhoeae, streptococci (termasuk Streptococcus faecalis dan S. pneumoniae), dan stafilokokus yang tak menghasilkan penisilinase. Diberikan secara oral.
|Trade names||Hundreds of names|
|By mouth, intravenous|
|Bioavailability||95% by mouth|
|Metabolism||less than 30% biotransformed in liver|
|Biological half-life||61.3 minutes|
|Synonyms||amoxicillin (INN, USAN); amoxycillin (BAN); amox|
|Chemical and physical data|
|Molar mass||365.4 g/mol|
|3D model (Jmol)|
Amoxicillin also spelled amoxycillin, is an antibiotic useful for the treatment of a number of bacterial infections. It is the first line treatment for middle ear infections. It may also be used for strep throat, pneumonia, skin infections, and urinary tract infections among others. It is taken by mouth, or less commonly by injection.
Common side effects include nausea and rash. It may also increase the risk of yeast infections and, when used in combination with clavulanic acid, diarrhea. It should not be used in those who are allergic to penicillin. While usable in those with kidney problems, the dose may need to be decreased. Its use in pregnancy and breastfeeding does not appear to be harmful.
Amoxicillin was discovered in 1958 and came into medical use in 1972. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is one of the most commonly prescribed antibiotics in children. Amoxicillin is available as a generic medication. It has a wholesale cost in the developing world of between 0.02 and 0.05 USD per pill. In the United States ten days of treatment costs about 16 USD.